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The GCF of 42 and 50 is: 2

List out the factors of the numbers given:

42: 1, 2, 3, 6, 7, 14, 21, 42

50: 1, 2, 5, 10, 25, 50

The common numbers between the two are 1 and 2, but the greatest number is 2, making it the greatest common factor.